性 别

女

通讯地址

遵义医科大学基础医学院

邮 编

563000

邮 箱

38779630@qq.com

职 称

讲师

职 务

无

简 介

王欣，女，中共党员，是全国本科毕业论文（设计）抽检评审专家库专家。从事自身免疫性甲状腺疾病和免疫性高致盲眼病的发病机制研究，主要探讨DNA甲基化、microRNA、SNP/CNV和Th17/Treg平衡在自身免疫性甲状腺疾病和免疫性高致盲眼病发生发展中的作用。主持贵州省卫健委科学技术基金项目1项，主持遵义市市校联合基金项目1项，主持完成院级教改项目1项，主持院级教改课题2项；参与完成省级科研项目和教改项目3项，参与国家重点研发计划、国家自然科学基金、贵州省科技厅/教育厅等项目5项；指导本科生主持省级大创项目2项；在Front Endocrinol、J Mol Med、Gene、Clin Immunol、Immun Inflamm Dis、《免疫学杂志》等杂志发表论文10余篇；获校级教学成果二等奖1项。

教育背景

2005.07，西南大学，获动物医学学士学位

2008.07，西南大学，获预防兽医学硕士学位

学术组织任职

Gene等SCI期刊审稿人

主讲课程

1.《基础医学概论》

2.《基础医学PBL》

3.《医学免疫学》

科研项目

1.贵州省卫健委科学技术基金项目：Th17/Treg相关基因多态性与贵州汉族人群Graves病易感性的关联研究，主持，在研

2.遵义市市校联合基金项目：IL-17F基因多态性在贵州汉族人群Graves病发生中的作用及分子机制研究，主持，在研

发表论文

近5年在Front Endocrinol、J Mol Med、Gene、Clin Immunol、Immun Inflamm Dis、《免疫学杂志》等杂志发表论文10余篇，部分代表性论文如下：

1.Tan Guiqin, Zheng Guangbing, Li Jiang,Zhu Yingping, Liang Zhongzhi, Li Hua, Yu Hongsong*, Wang Xin*（通讯作者）. Association of genetic variations in FoxP3 gene with Graves' disease in a Southwest Chinese Han population.Immun Inflamm Dis. 2023,11(10):e1046.

2.Tan Guiqin^#,Wang Xin^#(共同第一作者), Zheng Guangbing, Du Juan, Zhou Fangyu, Liang Zhongzhi, Wei Wenwen, Yu Hongsong*(corresponding author). Meta-analysis reveals significant association between FOXP3 polymorphisms and susceptibility to Graves' disease. J Int Med Res.2021, 49(4): 3000605211004199.

3. Du Juan,Wang Xin, Tan Guiqin, Wei Wenwen, Zhou Fangyu, Liang Zhongzhi, Li Hua, Yu Hongsong*. Predisposition to Graves' disease and Graves' ophthalmopathy by genetic variants of IL2RA. J Mol Med. 2021, 99(10): 1487-1495.

4. Ma Xiaomin,Wang Xin, Zheng Guangbing, Tan Guiqin, Zhou Fangyu, Wei Wenwen, Tian Dan,Yu Hongsong*. Critical Role of Gut Microbiota and Epigenetic Factors in the Pathogenesis of Behçet’s Disease. Front Cell Dev Biol. 2021, 9: 719235. (IF=6.684)

5. Zhou Fangyu^#, Liang Zhongzhi^#,Wang Xin, Tan Guiqin, Wei Wenwen, Zheng Guangbing, Ma Xiaomin, Tian Dan, Li Hua, Yu Hongsong*. The VDR gene confers a genetic predisposition to Graves' disease and Graves' ophthalmopathy in the Southwest Chinese Han population. Gene. 2021, 793:145750.

6. Zhou Fangyu,Wang Xin, Wang Lingjun, Sun Xin, Tan Guiqin, Wei Wenwen, Zheng Guangbing, Ma Xiaomin, Tian Dan,Yu Hongsong*. Genetics, Epigenetics, Cellular Immunology, and Gut Microbiota: Emerging Links With Graves' Disease. Front Cell Dev Biol. 2022, 9: 794912. (IF=6.684)

7. Du Juan,Wang Xin, Tan Guiqin, Liang Zhongzhi, Zhang Ze, Yu Hongsong*. The association between genetic polymorphisms of interleukin 23 receptor gene and the risk of rheumatoid arthritis: An updated meta-analysis.Clin Immunol. 2020, 210:108250.(IF=10.19)

8.Wang Yan, Ma Xiao-Min, Wang Xin, Sun Xin, Wang Ling-Jun, Li Xin-Qi, Liu Xiao-Yan, Yu Hong-Song*.Emerging Insights Into the Role of Epigenetics and Gut Microbiome in the Pathogenesis of Graves' Ophthalmopathy. Front Endocrinol. 2022, 12: 788535. (IF=5.555).

9. Li Qingxingzi, Liang Zhongzhi, Wang Xin, Zhou Fangyu, Ma Xiaomin, Wei Wenwen, Tian Dan, Yu Hongsong*. The emerging role of epigenetics and gut microbiota in Vogt-Koyanagi-Harada syndrome. Gene. 2022, 818:146222.

10.Fan Chenxi,Sun Xin,Wang Xin,Yu Hongsong*.Therapeutic potential of the chemical composition of Dendrobium nobile Lindl.Front Pharmacol. 2023,14:1163830.

教材、专著编写

无

奖 励

2016年，获校级教学成果二等奖